PPARδ Elicits Ligand-Independent Repression of Trefoil Factor Family to Limit Prostate Cancer Growth
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چکیده
منابع مشابه
Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth.
G-protein-coupled receptor (GPCR)-stimulated androgen-independent activation of androgen receptor (AR) contributes to acquisition of a hormone-refractory phenotype by prostate cancer. We previously reported that regulator of G-protein signaling (RGS) 2, an inhibitor of GPCRs, inhibits androgen-independent AR activation (Cao et al., Oncogene 2006;25:3719-34). Here, we show reduced RGS2 protein e...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2017
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-17-0908